11/10/2023 0 Comments Hydroxocobalamin cyanokitThe Dutch National Health Council therefore decided not to determine a safe upper intake level for vitamin B12. No single case has been found in medical literature in the past 60 years. In all that time harmful effects have never been shown from overdose. Usually per injection and often lifelong, as a deficiency is mostly caused by an irreversible absorption disorder. Since then numerous patients have been treated with high dose vitamin B12 worldwide. More than 20 years later the substance that was responsible for that was isolated from liver extract: vitamin B12 or cobalamin. In 1926 it was discovered that patients with pernicious anaemia could be saved from a certain death by eating a pound of raw liver a day. Clinical research and the treatment for cyanide poisoning have shown that even extremely high doses of vitamin B12 and the serum values that go with it are harmless.Ī decennia long history of safe treatment.The Dutch National Health Counsel and the Regional Disciplinary Medical Board of Eindhoven have stated clearly that vitamin B12 is non-toxic.For over 60 years high dose vitamin B12 treatment has been used without any signs of the danger of an overdose. It is very clear this fear of overdosing is based on a misunderstanding.As a result, symptoms can reoccur again and again and even become irreversible.Out of fear of overdosing vitamin B12, treatment is often reduced to below the frequency that is needed by the patient, or, even worse, treatment is stopped completely.
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